Multi-Component HPLC Analysis and Antioxidant Activity Characterization of Extracts from Dipsacus sativus (Linn.) Honck

作者

Yang, BX;Feng, X;Xu, JK;Lei, HX;Zhang, L

作者单位

[Yang, Bingxian; Xu, Jinke; Zhang, Lin] Zhejiang Univ, Minist Educ, Key Lab Biomed Engn, Dept Biomed Engn, Hangzhou 310027, Zhejiang, Peoples R China.;-;[Feng, Xiao] Shandong Prov Hosp, Jinan, Peoples R China.;-;[Xu, Jinke] Shandong Ctr Dis Control & Prevent, Jinan, Peoples R China.;-;[Lei, Houxing] Lishui Peoples Hosp, Lishui, Peoples R China.

摘要

A highly reliable high-performance liquid chromatography method was developed and validated for determining quality of extracts from the leaves of Dipsacus sativus (Linn.) Honck. Under optimum conditions, the chromatography profile of eight compounds was collected, with compound saponarin as marker. The analysis results indicated that saponarin and isovitexin were the main active components. Pharmacological experiments proved that extracts from the leaves showed significant antioxidant activity. This work could serve to validate the usefulness of high-performance liquid chromatography analyses in traditional Chinese medicine.

关键词

PERFORMANCE LIQUID-CHROMATOGRAPHY; TRADITIONAL CHINESE MEDICINE; CHEMICAL-ANALYSIS; QUALITY-CONTROL; ARRAY DETECTOR; FLAVONOIDS; LEAVES; SPECTROMETRY; RISK

基本信息

所属机构:

归属医师: 冯晓

UT：000375764500006

刊名:INTERNATIONAL JOURNAL OF FOOD PROPERTIES

年，卷(期):2016年19卷5期

页码：1000-1006

DOI：10.1080/10942912.2015.1052503

附件：

收录: SCIE