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Ideal cardiovascular health behaviors and factors prevent the development of hypertension in prehypertensive subjects

    作者

    Gao, JS;Sun, H;Liang, X;Gao, M;Zhao, HT;Qi, YH;Wang, YX;Liu, Y;Li, JF;Zhu, Y;Zhao, Y;Wang, W;Ma, LY;Wu, SL

    作者单位

    [Gao, Jingsheng; Liang, Xin; Gao, Ming; Zhao, Hongtao; Qi, Yanhong; Wang, Yanxiu; Liu, Ying; Li, Jinfeng; Zhu, Ying; Wu, Shouling] Hebei United Univ, Kailuan Hosp, Dept Cardiol, Tangshan 063000, Peoples R China.;-;[Sun, Hui] Shandong Univ, Dept Cardiol, Jinan Cent Hosp, Jinan 250100, Shandong, Peoples R China.;-;[Zhao, Yong] Shandong Univ, Dept Geriatr Cardiol, Prov Hosp, Jinan 250100, Shandong, Peoples R China.;-;[Wang, Wen; Ma, Liyuan] Cardiovasc Inst, Dept Evidence Based Med, Beijing, Peoples R China.;-;[Wang, Wen; Ma, Liyuan] Fuwai Hosp, Beijing, Peoples R China.

    摘要

    Background: Seven ideal health metrics were defined by AHA to monitor cardiovascular health. This study aimed to investigate the impact of ideal cardiovascular health behaviors and factors on the development of hypertension in prehypertensive subjects. Methods: Thirty-two thousand eight-hundred and eighty-seven participants with prehypertension were included in the study after excluding for preexisting stroke, myocardial infarction or malignancy. Cox proportional hazards regression was used to calculate hazard ratios and 95% confidence intervals [CI] for the development of hypertension. Results: During a follow-up of 52.2 months, 15500 prehypertensive participants developed hypertension. The cumulative incidence of hypertension decreased with the number of ideal health metrics increased. It was 78.61%, 71.08%, 63.15%, 56.07% and 61.62% in prehypertensive individuals carrying 1, 2, 3, 4 and 5 ideal health behaviors or factors, respectively. After adjustment for age, gender, family history of hypertension, alcohol consumption, resting heart rate, plasma triglyceride, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, and high-sensitivity C-reactive protein, the risk ratios of incident hypertension in the subjects who carried 2, 3, 4, and 5 ideal health metrics were 0.833 (95%CI: 0.789-0.880), 0.710 (95%CI: 0.672-0.749), 0.604 (95%CI: 0.568-0.642), and 0.581 (95%CI: 0.524-0.643), respectively, in comparison to those with 1 ideal health metric. A similar trend was also observed in male and female populations. Poor health metrics, including body mass index, diet (salt intake), physical activity, total cholesterol, and smoking, were predictors for the development of hypertension in prehypertensive individuals. Conclusion: Ideal cardiovascular health behaviors and factors are protective factors to prevent the progression from prehypertension to hypertension.

    关键词

    LIAONING PROVINCE; PREVALENCE; PREDICTORS; RISK; ASSOCIATION; PROGRESSION; POPULATION; COHORT
基本信息

  • 所属机构:

    归属医师: 赵勇

    PMID:26114351

    UT:000364482900007

    刊名:CLINICAL AND EXPERIMENTAL HYPERTENSION

    年,卷(期):2015年37卷8期

    页码:650-655

    DOI:10.3109/10641963.2015.1047938

    附件:

    收录:   SCIE