A Review of Collagen Cross-Linking in Cornea and Sclera

作者

Zhang, X;Tao, XC;Zhang, J;Li, ZW;Xu, YY;Wang, YM;Zhang, CX;Mu, GY

作者单位

[Zhang, Xiao; Tao, Xiang-chen; Li, Zhi-wei; Xu, Yan-yun; Wang, Yu-meng; Zhang, Chun-xiao; Mu, Guo-ying] Shandong Univ, Shandong Prov Hosp, Dept Ophthalmol, Jinan 250000, Shandong, Peoples R China.;-;[Zhang, Jian] Zibo Eye Hosp, Zibo 255100, Shandong, Peoples R China.

摘要

Riboflavin/UVA cross-linking is a technique introduced in the past decades for the treatment of keratoconus, keratectasia, and infectious keratitis. Its efficacy and safety have been investigated with clinical and laboratory studies since its first clinical application by Wollensak for the treatment of keratoconus. Although its complications are encountered during clinical practice, such as infection inducing risk, minimal invasion merits a further investigation on its future application in clinical practice. Recently, collagen cross-linking in sclera shows a promising prospect. In present study, we summarized the representative studies describing the clinical and laboratory application of collagen cross-linking published in past decades and provided our opinion on the positive and negative results of cross-linking in the treatment of ophthalmic disorders.

关键词

HYPOOSMOLAR RIBOFLAVIN SOLUTION; IN-SITU KERATOMILEUSIS; INTRACORNEAL RING SEGMENTS; MOLECULAR-WEIGHT COMPOUNDS; ULTRAVIOLET-A LIGHT; BENZALKONIUM CHLORIDE; MICROBIAL KERATITIS; THIN CORNEAS; PROGRESSIVE KERATOCONUS; ACANTHAMOEBA-KERATITIS

基本信息

所属机构:

归属医师: 张春晓牟国营陶祥臣李志伟

UT：000352883700001

刊名:JOURNAL OF OPHTHALMOLOGY

年，卷(期):2015年

DOI：10.1155/2015/289467

附件：

收录: SCIE