Second-generation cryoballoon vs. contact-force sensing radiofrequency catheter ablation in atrial fibrillation: a meta-analysis of randomized controlled trials
作者
Wang, Y; Wang, W; Yao, JM; Chen, LH; Yi, SL
作者单位
[Wang, Yang] Qingdao Univ, Dept Radiat Oncol, Affiliated Yantai Yuhuangding Hosp, Yantai, Peoples R China; [Wang, Wei; Chen, Lianghua; Yi, Shaolei] Shandong First Med Univ, Dept Cardiol, Shandong Prov Hosp, Jinan, Peoples R China; [Wang, Wei; Yi, Shaolei] Shandong Univ, Dept Cardiol, Shandong Prov Hosp, 324 Jingwulu, Jinan 250010, Shandong, Peoples R China; [Yao, Jianming] Jinan Municipal Hosp Tradit Chinese Med, Dept Cardiol, Jinan, Peoples R China
摘要
Objectives It is imperative to understand the influence of second-generation cryoballoon (CB-2) and contact-force sensing radiofrequency ablation (CF-RF) on clinical outcomes in atrial fibrillation (AF). This updated meta-analysis of randomized controlled trials (RCTs) examined the efficacy and safety of CB-2 vs. CF-RF in patients with AF. Methods RCTs on the use of CB-2 vs. CF-RF in patients with AF were included. The primary outcome was the recurrence of AF, and the key secondary outcomes included serious complications, acute pulmonary vein isolation (PVI), procedure duration, and fluoroscopy time. Results A total of 261 articles were identified, and five studies with a total of 845 participants were included in the study. A total of 93% of participants had paroxysmal AF, 7% of participants had persistent AF, and none of participants had permanent AF. There were 499 participants in the CB-2 arm and 346 in the CF-RF arm. AF recurrence was comparable in the CB-2 group (30.3%) and the CF-RF group (29.2%) (OR = 0.93; 95%CI = 0.56-1.54;P = 0.79;I-2 = 48%). There were no statistical differences in acute PVI (P = 0.92;I-2 = 0%) and serious complications (P = 0.87;I-2 = 47%) between the two groups. The procedure duration was shorter in the CB-2 group than in the CF-RF group (MD = - 13.39; 95%CI = - 15.58, - 7.19;P < 0.0001;I-2 = 59%). Conclusion Our study demonstrated that CB-2 and CF-RF had comparable recurrences of AF and similar incidences of serious complications in AF patients during the ablation process.
关键词
PULMONARY VEIN ISOLATION
基本信息
