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The toxicity and safety of traditional Chinese medicines: Please treat with rationality

    作者

    Cai, PP; Qiu, H; Qi, FH; Zhang, XY

    作者单位

    [Cai, Pingping; Qi, Fanghua; Zhang, Xiaoyi] Shandong Univ, Shandong Prov Hosp, Dept Tradit Chinese Med, 324 Jingwuweigi Rd, Jinan 250021, Shandong, Peoples R China; [Qiu, Hua] Jinan Municipal Hosp Tradit Chinese Med, Dept Gynecol, Jinan, Shandong, Peoples R China

    摘要

    For a long time, many people have believed that traditional Chinese medicines (TCMs) arc safe because they derive from natural products. However, this belief has been greatly challenged in recent years especially after some reports on aristolochic acid involved in the genesis of cancer. According to the Chinese pharmacopoeia, many TCMs are known to be toxic, causing damage to the nervous, liver, renal, respiratory, and reproductive system. How to reduce the toxicity of TCMs and how to avoid abuse of TCMs in daily practice is the question? Here, we will give a brief summary and some tips on these issues. First, the accurate differentiation of a specific syndrome is the foundation of an effective and individualized treatment strategy, as well as the key to applying TCMs. Second, through standard processing, proper compatibility, rational decoction, and appropriate dose for TCMs, the harm of TCMs can be effectively avoided. Third, it should be remembered that Chinese herbs cannot be taken continuously as dietary supplements. Finally, Chinese patent medicines should be used with caution. In addition, the dosage of TCMs should not exceed the limit prescribed by the current China Pharmacopoeia, which will ensure the balance of efficacy and toxicity. Taken together, it is necessary to treat the toxicity and safety of TCMs with rationality. The more toxicity we can find, the more safety patients will have.

    关键词

    FUZI LATERAL ROOT; ACONITUM-CARMICHAELI; HERBAL MEDICINES; PHYTOCHEMISTRY; TOXICOLOGY
基本信息

  • 所属机构:中医科

    归属医师: 张小艺 蔡平平 齐芳华

    PMID:31564696

    UT:000494952600001

    刊名:BIOSCIENCE TRENDS

    年,卷(期):2019年13卷5期

    页码:367-373

    DOI:10.5582/bst.2019.01244

    附件: other

    收录:   SCIE