Prevalence and transmission of mobilized colistin resistance (mcr-1) gene positive Escherichia coli in healthy rural residents in Shandong province, China

作者

Huang, SM; Wang, S; Li, Y; Fang, M; Kou, ZQ; Chen, BL; Xu, LC; Bi, ZW; Xu, H; Chi, XH; Bi, ZQ

作者单位

[Huang, Shumei] Shandong Univ, Sch Publ Hlth, Jinan 250012, Peoples R China; [Wang, Shuang; Li, Yan; Fang, Ming; Kou, Zengqiang; Chen, Baoli; Xu, Liuchen; Bi, Zhenqiang] Bacterial Infect Dis Control Inst, Shandong Ctr Dis Control & Prevent, Jinan 250014, Peoples R China; [Xu, Hao] Zhejiang Univ, State Key Lab Diag & Treatment Infect Dis, Sch Med, Affiliated Hosp 1, Hangzhou 310003, Peoples R China; [Chi, Xiaohui] Zhejiang Univ, Dept Publ Hlth, Hangzhou 310058, Peoples R China; [Bi, Zhenwang] Shandong First Med Univ, Shandong Prov Hosp, Jinan 250062, Peoples R China; [Bi, Zhenwang] Shandong Acad Med Sci, Jinan 250062, Peoples R China

摘要

This study was conducted to explore the prevalence and transmission of mcr-1 Escherichia coli among healthy rural residents in Shandong, China, and to provide theoretical basis for the prevention and control of spread and treatment of multi-drug resistant Escherichia coli. A total of 218 healthy residents from 3 villages in Guan County, Shandong Province, China were included in this study, and their fecal samples were collected. Colistin-resistant Escherichia coli were selected, and their drug sensitivity and plasmids' transferability were measured. After analysis, some conclusions can be drawn. The colistin-resistant Escherichia coli, most strains of which are MDROs, is common and highly transmissible in healthy residents in rural areas in China. Interventions should be implemented to prevent the spread of colistin-resistant Escherichia coli through health education and tighter regulation of antibiotics.

关键词

基本信息

所属机构:

归属医师: 毕振旺

PMID：34592562

UT：000711704700008

刊名:MICROBIOLOGICAL RESEARCH

年，卷(期):2021年253卷期

页码：-null

DOI：10.1016/j.micres.2021.126881

附件： other

收录: SCIE