在结果中搜索
成果类型 (Type)
- 已选条件:
Prognosis of adenoid cystic carcinoma in head and neck region treated with different regimens-A single-centre study
Cheng, YT; Xu, L; Chen, ZW; Wu, HW; Zou, HW; Zhang, TQ; Liu, GJ; Liu, ZX; Yin, CW; Ma, L; Zhang, SZ; Li, WG; Huang, SY; Zhang, DS
CANCER MEDICINE 2022年 页码:-null
无关键词信息
Background No study has evaluated the impact of regimen on recurrence, metastasis and survival in patients with adenoid cystic carcinoma (ACC). The present study aimed to compare the efficacy of radioactive seed implantation and other regimens in treating ACC, so as to investigate the clinical applicability of radioactive seed implantation and determine the indications for this regimen. Methods A total of 188 patients with ACC in oromaxillofacial region were allocated to four groups according to the treatment regimen: group 1 was treated with a combination of surgery and I-125 seed therapy, group 2 with a combination of surgery and external radiotherapy, group 3 with surgery, whereas group 4 was untreated. The Kaplan-Meier method was used to assess the survival rates, and the Cox regression analyses were used to identify the associated prognostic factors. Results The overall survival rates of 188 patients and groups 1, 2, 3 and 4 were 85.7%, 75%, 68.2% and 37.5%, respectively. Cox regression analysis revealed that age, T stage, N stage and regimen were independent prognostic factors of survival. Amongst patients with primary ACC, the efficacy of radioactive seed implantation was higher in those with perineural invasion than in those without. Conclusion Patient age, T stage, N stage and regimen are independent prognostic factors of survival in patients with ACC. Patients treated with surgery combined with postoperative I-125 seed radiotherapy have a higher overall survival rate, and those with perineural invasion are more suitable for radioactive seed implantation therapy.
头颈部腺样囊性癌预后分析:单中心经验
程煜天;徐乐;马利;吴海威;陈占伟;邹虎威;张天奇;刘桂军;刘振兴;尹长伟;李文刚;张世周;黄圣运;张东升;
中国口腔颌面外科杂志 2023年 21卷05期 页码:467-471 影响因子:0.611
腺样囊性癌;;头颈部;;预后分析
目的:通过探讨头颈部腺样囊性癌(adenoid cystic carcinoma, ACC)的临床特点,分析影响其生存、复发、转移等预后的因素。方法:回顾性收集2010年1月—2020年12月在山东第一医科大学附属省立医院口腔颌面外科就诊的188例腺样囊性癌患者的临床资料,进行门诊或电话随访,采用SPSS 26.0软件包中的Kaplan-Meier法评估生存情况,应用Cox回归分析对其相关预后因素进行分析。结果:188例患者总体生存率为76.6%,其中因复发死亡13.3%,远处转移死亡10.1%。复发率23.9%,转移率10.1%。其中复发患者生存率42.2%,转移患者生存率为68.4%。Cox回归分析结果显示,年龄、肿瘤原发灶大小、区域淋巴结转移和治疗方式为影响患者生存率的预后因素。结论:患者年龄、T分期、N分期和治疗方式为影响腺样囊性癌患者生存率的预后因素,患者年龄、神经侵犯为影响腺样囊性癌患者复发的预后因素,患者N分期为影响腺样囊性癌患者转移的预后因素。
每页: 条
- <<
- <
- >
- >>